Summary
An analytical method was developed to analyze 5 phthalate esters (dimethylphthalate, diethylphthalate, di-n-butylphthalate, butylbenzylphthalate, di(2-ethylhexyl)phthalate), nonylphenol, bisphenol A and BADGE (Bisphenol A diglycyleter) in distribution and bottled water. They are all industrial chemicals used in the manufacture of epoxy resins or paints, polycarbonate and polyethylene plastics (global production of phthalates over 4 Mton/year) or surfactants and have been classified as persistent, with high migration potential from plastic containers and with endocrine disrupting properties. The present paper reports a specific extraction protocol using solid phase extraction with Oasis 60 mg or C18 cartridges, followed by gas chromalography coupled to mass spectrometric detection using an appropriate surrogate and internal standard for process control. Quality parameters are reported, making special emphasis to limits of detection, reproducibility and blank analysis, which permitted to detect ng L−1 concentrations. In an application step, the method was used to determine target compounds in 7 distribution water and 9 mineral water bottled in polyethylene, polyethyleneter phthalate and glass containers which were analysed upon purchase and after 10 week storage at temperatures up to 30 °C. Distribution water coming from different aquifers which at some point are in contact with plastic or painted concrete reservoirs and pipes, contained dimethylphthalate, diethylphtalate, nonylphenol, buthylbenzylphthtalate and DEHP at concentrations ranging from 0.005 to 0.331 μgL−1, depending on the sampled crea whereas bottled water showed levels up to 1.7 μg L−1 of some of the studied compounds, attributed to 10 week storage conditions.
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References
Sha, R.M.Pure & Appli. Chem. 1998,70, 1685.
Rivas, A.; Olea, N.; Olea-Serrano, F.TRAC 1997,16(10), 613.
Hylland, K.; Haux, C.TRAC 1997,6(10), 606.
Groshart, Ch.; Okkerman, P.C. Toward the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: Preparation of a candidate list of substances as a basis for priority setting. Final report (incorporating corrigenda to final report dated 21 June, 2000). European Commission DG Env.
Field, J.A.; Reed, R.L.Environ. Sci. Technol. 1996,30, 3544.
Castillo, M.; Barceló, D.Anal. Chem.,1999,71(17), 3769.
Petrovic, M.; Barceló, D.Anal. Chem. 2000,72(19), 4560.
Guenther, K.; Heinke, V.; Thiele, B.; Kleist, E.; Prast, H.; Raecker, T.Environ. Sci. Technol. 2002,36, 1676.
Summerfield, W.; Goodson, A.; Cooper, I.Food Additives and Contaminants 1998, (15/7), 818.
Brotons, J.A.; Olea-Serrano, M.F.; Villalobos, M.; Pedraza, V.; Olea, N.Environmental Health Prespectives 1995,103(6), 608.
Romero, J.; Ventura, F.; Gomez, M.J. Chromatogr. Sci. 2002,40, 191.
Ikem, A.; Odueyungbo, S.; Egiebor, N.O.; Nyabor, K.Sci. Total Environ. 2002,285, 165.
Talmage, S.S. Environmental and Human Safety of Major Surfactants, Lewis Publishers, Boca Raton,1994.
Moore, N.P.Reproductive Toxicol. 2002,14, 183.
Hojslev Petersen, J.; Breindahal, T.Food Additives and Contam. 2002,17(2), 133.
Balafas, D.; Shaw, K.J.; Whitfield, F.B.Food Chemistry 1999,65, 279.
Peñalver, A.; Pocurull, E.; Borrull, F.; Marcé, R.M.J. Chromatogr. A 2000,872, 191.
Del Olmo, M.; Gonzalez Casado, A.; Navas, N.A.; Vilchez, J.L.Anal. Chim. Acta 1997,345, 87.
Young, M.S.; Phillips, D.J.; Romano, J.; Krol, J. (corporate source Waters Corporation, Milford, MA 01757, USA. Prepr. Ext. Abstr. ACS Nalt. Meet., Am. Chem. Soc., Div. Environ. Chem., 40(1), 92–93 (English) 2000 American Chemical Society, Division of Environmental Chemistry.
Peñalver, A.; Pocurull, E.; Borrull, F.; Marce, R.M.J. Chromatogr. A 2001,922, 377.
Staples, C.A.; Parkerton, T.F.; Peterson, D.R.Chemosphere 2000,40, 885.
Latorre, A.; Lacorte, S.; Barceló, D.Chromatographia 2003,57(1/2), 111.
Sonnenschein, C.; Soto, A.; Fernandez, M.; Olea, N.; Olea-Serrano, F.; Ruiz-Lopez, M.Clin. Chem. 1995,41, 1888.
Ben-Jonathan, N.; Steinmetz, R.TEM 1998,9, 3.
Wilkinson, C.F.; Lamb, IV J.C.Regulatory Toxicology and Pharmacology 1999,30, 140.
Earls, A.O.; Axford, I.P.; Braybrook, J.H.J. Chromatogr. A 2003,983, 237.
Ghijsen, R.T.; Hoogenboezen, W. Endocrine disrupting compounds in the Rhine and Meuse basin. Occurrence in surface, process and drinking water. Association of River Waterworks,2000.
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Casajuana, N., Lacorte, S. Presence and release of phthalic esters and other endocrine disrupting compounds in drinking water. Chromatographia 57, 649–655 (2003). https://doi.org/10.1007/BF02491744
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DOI: https://doi.org/10.1007/BF02491744