Abstract
Continuous negative extrathoracic pressure (CNEP) has been recently reintroduced as therapy for respiratory failure. To determine its effects on cardiac output a pilot study was performed in ten patients aged 2 months-3 years (meadian 4 months). All had chronic respiratory failure (seven with bronchopulmonary dysplasia). Five were breathing spontaneously and five were intubated and undergoing intermittent positive pressure ventilation. Transcutaneous oxygen saturation andPCO2, together with ECG were continuously monitored. Pulmonary artery blood flow velocity was measured noninvasively using pulsed wave Doppler. The 95% confidence intervals for the changes with and without CNEP in spontaneously breathing and ventilated patients showed no statistically significant changes in heart rate, O2 saturation, transcutaneousPCO2 or cardiac output. This study shows that the use of CNEP, administered in a tank respirator, does not lead to large changes in cardiac output.
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Abbreviations
- CNEP:
-
continuous negative extrathoracic pressure
- CO:
-
cardiac output
- IPPV:
-
intermittent positive pressure ventilation
- PEEP:
-
positive end expiratory pressure
- PIP:
-
peak inspiratory pressure
- PVR:
-
pulmonary vascular resistance
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Raine, J., Redington, A.N., Benatar, A. et al. Continuous negative extrathoracic pressure and cardiac output —a pilot study. Eur J Pediatr 152, 595–598 (1993). https://doi.org/10.1007/BF01954088
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DOI: https://doi.org/10.1007/BF01954088