Abstract
Over a 14-month period, 415 clinical isolates of coryneform gram-positive rods were recovered from various sources and identified to the species level according to recent identification schemes.Corynebacterium urealyticum, Corynebacterium striatum, Corynebacterium amycolatum, andCorynebacterium jeikeium predominated, accounting for 63% of all isolates.Corynebacterium accolens, Corynebacterium striatum, Corynebacterium argentoratense, Corynebacterium propinquum andCorynebacterium pseudodiphtheriticum were mostly recovered from the respiratory tract, whereasCorynebacterium afermentans, CDC group G, andCorynebacterium jeikeium were mainly isolated from blood. None of the isolates was identified asCorynebacterium diphtheriae orCorynebacterium xerosis. Ampicillin resistance was detected inCorynebacterium jeikeium (96%) andCorynebacterium urealyticum (99%) and varied amongCorynebacterium amycolatum (56%) and CDC group G (26%). These data emphasize the need for an accurate identification of coryneform organisms at the species level and for antimicrobial susceptibility testing of these organisms.
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References
Coyle MB, Lipsky BJ: Coryneform bacteria in infectious diseases: clinical and laboratory aspects. Clinical Microbiology Reviews 1990, 3: 227–246.
Colt HG, Morris JF, Marston BJ, Sewell DL: Necrotizing tracheitis caused byCorynebacterium pseudodiphtheriticum: unique case and review. Reviews of Infectious Diseases 1991, 13: 73–76.
Sewell DL, Coyle MB, Funke G: Prosthetic valve endocarditis caused byCorynebacterium afermentans subsp.lipophilum (CDC coryneform group ANF-1). Journal of Clinical Microbiology 1995, 33: 759–761.
Soriano F, Fernandez-Roblas R: Infections caused by antibiotic-resistantCorynebacterium group D-2. European Journal of Clinical Microbiology & Infectious Diseases 1988, 7: 337–341.
Hollis DG, Weaver RE: Gram-positive organisms: a guide to identification. Centers for Disease Control, Atlanta, GA, 1981.
Clarridge JE, Spiegel CA:Corynebacterium and miscellaneous irregular gram-positive rods,Erysipelothrix, andGardnerella. In: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (ed): Manual of clinical microbiology. American Society for Microbiology, Washington DC, 1995, p. 357–378.
Funke G, von Graevenitz A, Weiss N: Primary identification ofAureobacterium spp. isolated from clinical specimens as “Corynebacterium aquaticum”. Journal of Clinical Microbiology 1994, 32: 2686–2691.
Funke G, Falsen E, Barreau C: Primary identification ofMicrobacterium spp. encountered in clinical specimens as CDC coryneform group A-4 and A-5 bacteria. Journal of Clinical Microbiology 1995, 33: 188–192.
Riegel P, de Briel D, Prévost G, Jehl F, Monteil H, Minck R: Taxonomic study ofCorynebacterium group ANF-1: proposal ofCorynebacterium afermentans sp. nov. containing the subspecies C.afermentans subsp.afermentans subsp. nov. and C.afermentans subsp.lipophilum subsp. nov. International Journal of Systematic Bacteriology 1993, 43: 287–292.
Funke G, Lawson PA, Collins MD: Heterogeneity within human-derived Centers for Disease Control and Prevention (CDC) coryneform group ANF-1-like bacteria and description ofCorynebacterium auris sp. nov. International Journal of Systematic Bacteriology 1995, 45: 735–739.
Riegel P, de Briel D, Prévost G, Jehl F, Monteil H: Proposal ofCorynebacterium propinquum sp. nov. forCorynebacterium group ANF-3 strains. FEMS Microbiology Letters 1993, 113: 229–234.
Riegel P, Ruimy R, de Briel D, Prévost G, Jehl F, Christen R, Monteil H: Genomic diversity and phylogenetic relationships among lipid-requiring diphtheroids from humans and characterization ofCorynebacterium macginleyi sp. nov. International Journal of Systematic Bacteriology 1995, 45: 128–133.
Riegel P, Ruimy R, de Briel D, Prévost G, Jehl F, Bimet F, Christen R, Monteil H:Corynebacterium argentoratense sp. nov. from the human throat. International Journal of Systematic Bacteriology 1995, 45: 533–537.
Riegel P, Ruimy R, de Briel D, Prévost G, Jehl F, Bimet F, Christen R, Monteil H:Corynebacterium seminale sp. nov., a new species associated with genital infections in male patients. Journal of Clinical Microbiology 1995, 33: 2244–2249.
Funke G, Bernard KA, Bucher C, Pfyffer GE, Collins MD:Corynebacterium glucuronolyticum sp. nov. isolated from male patients with genitourinary infections. Medical Microbiology Letters 1995, 4: 204–215.
Lortholary O, Buu-HoÏ A, Fagon JY, Pierre J, Slama M, Gutmann L, Acar JF: Mediastinis due to multiply resistantCorynebacterium xerosis. Clinical Infectious Diseases 1993, 16: 172.
Wallet F, Marquette CH, Courcol R: MultiresistantCorynebacterium xerosis as a cause of pneumonia in a patient with acute leukemia. Clinical Infectious Diseases 1994, 18: 845–846.
De Briel D, Langs JC, Rougeron G, Chabot P, Le Faou A: Multiresistant corynebacteria in bacteriuria: a comparative study of the role ofCorynebacterium group D2 andCorynebacterium jeikeium. Journal of Hospital Infection 1991, 17: 35–43.
Société FranÇaise de Microbiologie: Communiqué 1995 du comité de l'antibiogramme. Pathologie Biologie 1995, 43: I-VIII.
Collins MD, Burton RA, Jones D:Corynebacterium amycolatum sp. nov., a new mycolic acid-lessCorynebacterium species from human skins. FEMS Microbiology Letters 1988, 49: 349–352.
Barreau C, Bimet F, Kiredjian M, Roullion N, Bizet C: Comparative chemotaxonomic studies of mycolic acidfree coryneform bacteria of human origin. Journal of Clinical Microbiology 1993, 31: 2085–2090.
Soriano F, Zapardiel J, Nieto E: Antimicrobial susceptibilities ofCorynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents. Antimicrobial Agents and Chemotherapy 1995, 39: 208–214.
Williams DY, Selepak ST, Gill VJ: Identification of clinical isolates of nondiphtherialCorynebacterium species and their antibiotic susceptibility patterns. Diagnostic Microbiology and Infectious Disease 1993, 17: 23–28.
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Riegel, P., Ruimy, R., Christen, R. et al. Species identities and antimicrobial susceptibilities of corynebacteria isolated from various clinical sources. Eur. J. Clin. Microbiol. Infect. Dis. 15, 657–662 (1996). https://doi.org/10.1007/BF01691153
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DOI: https://doi.org/10.1007/BF01691153