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Reduction of atherogenic risk factors by short-term weight reduction

Evidence of the efficacy of National Cholesterol Education Program guidelines for the obese

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Summary

Five hundred and ninety-nine overweight patients participated for at least 4 weeks in the weight reducing and physical activity promoting Diet and Fitness Center program at Duke University. Twenty-three percent were diabetic and 49% hypertensive. With only modest weight loss (11.8 kg in males and 8.2 kg in females) abnormal levels of blood pressure, fasting blood suger, total cholesterol, LDL-cholesterol and triglycerides normalized. It was very rewarding to see these results achieved in a very limited period of time. Improvements in the lipid profile were consistent with the predicted outcome of obesity treatment stated by the National Cholesterol Education Program guidelines.

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Abbreviations

DFC:

Diet and Fitness Center

TC:

total cholesterol

TG:

triglycerides

HDL-C:

high density lipoprotein cholesterol

LDL-C:

low density lipoprotein cholesterol

SBP:

systolic blood pressure

DBP:

diastolic blood pressure

References

  1. Brownell KD, Stunkard AJ (1981) Differential Changes in Plasma High Density Lipoprotein-Cholesterol Levels in Obese Men and Women During Weight Reduction. Arch Intern Med 141:1142–1146

    Google Scholar 

  2. Heyden S, Heiss G, Bartel AG, Hames CG (1980) Sex Differences in Coronary Mortality Among Diabetics in Evans County, Georgia. J Chron Dis 33:275–282

    Google Scholar 

  3. Heyden S, Schneider KA, Fodor JG (1989) Diabetes Continues to Pose High Risk for Ischemic Heart Disease — Lipid and Lipoprotein Abnormalities in Diabetic Patients. Arztl Lab 35:183–187

    Google Scholar 

  4. Heyden S, Schneider KA (1990) Obesity and Hypertension. J Human Hypertension 4:431–435

    Google Scholar 

  5. Manson JE, Colditz GA, Stampfer MJ, Willett WC, Rosney B, Monson RR, Speizer FE, Hennekens CH (1990) A Prospective Study of Obesity and Risk of Coronary Heart Disease in Women. N Engl J Med 322:882–889

    Google Scholar 

  6. Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High blood Cholesterol in Adults (1988) Arch Inter Med 148:36–69

    Google Scholar 

  7. Rossner S, Bjorrel H (1987) Early and Late Effects of Weight Loss on Liproprotein Metabolism in Severe Obesity. Atherosclerosis 64:125–130

    Google Scholar 

  8. Stevenson DW, Darga LL, Spafford TR, Ahmad N, Lucas CP (1987) Variables Effects of Weight Loss on Serum Lipids and Lipoproteins in Obese Patients. Int J Obesity 12:495–502

    Google Scholar 

  9. Streja DA, Boyko E, Rabkin SW (1980) Changes in Plasma High-Density Lipoprotein Cholesterol Concentration After Weight Reduction in Grossly Overweight Subjects. Br Med J 281:770–772

    Google Scholar 

  10. Thompson DD, Jeffery RW, Wing RR, Wood PD (1979) Unexpected Decrease in Plasma High Density Lipoprotein Cholesterol with Weight Loss. Am J Clin Nutr 32:2016–2021

    Google Scholar 

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Schieffer, B., Moore, D., Funke, E. et al. Reduction of atherogenic risk factors by short-term weight reduction. Klin Wochenschr 69, 163–167 (1991). https://doi.org/10.1007/BF01665860

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  • DOI: https://doi.org/10.1007/BF01665860

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