Summary
The cerebral angiograms of patients with cerebrovascular diseases, head injury and intracranial tumours obtained under normal and pharmacologically increased blood pressure were compared. Changes in cerebral blood flow, circulation time and arterial diameter were examined. CBF was measured by a semiquantitative densitometric method, arterial diameter by a split-image focusing technique.
The majority of patients with normal angiograms showed a virtually constant CBF and circulation time, while there was a slight constriction of the arteries. The functional tests during cerebral angiography revealed disturbances of autoregulation in patients with acute cerebrovascular diseases or with intracranial tumours.
Zusammenfassung
An Patienten mit normalen und pathologischen angiographischen Befunden wurden Serienangiogramme bei normalem und medikamentös gesteigertem Blutdruck durchgeführt. Die Auswertung der Angiogramme erfolgte hinsichtlich Strömungsgröße, Gefäßdurchmesser und Zirkulationszeit. Die Durchströmung wurde mit Hilfe einer semiquantitativen densitometrischen Methode bestimmt. Die Messung des Gefäßdurchmessers erfolgte mit einem Schnittbilddickenmesser.
Die meisten Patienten zeigten bei Blutdrucksteigerung eine Konstanthaltung der Strömung und der Zirkulationszeiten, während sich die Arterien meßbar kontrahierten. Bei Patienten mit frischen cerebrovasculären Insulten und Hirntumoren ließen sich mit den angiographischen Belastungstesten Störungen der Autoregulation nachweisen.
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Magun, JG. The effect of pharmacologically increased blood pressure on brain circulation. J Neurol 204, 107–134 (1973). https://doi.org/10.1007/BF00315937
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DOI: https://doi.org/10.1007/BF00315937