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Differential executive control impairments in early Parkinson’s disease

  • Chapter
Focus on Extrapyramidal Dysfunction

Part of the book series: Journal of Neural Transmission. Supplementa ((NEURAL SUPPL,volume 68))

Summary

Investigations concerning cogmnve function s in early PD have revealed memory and executive function deficits related to dysfunction of fronto-striatal circuitry. Despite the range of data base, many previous investigations are limited because of methodological questions and inconsistencies. Thus the pattern of executive function impairments in early PD is far from being established. In the present investigation, twenty PD patients in early stages of the disease were compared to control subjects on a comprehen sive neuropsychological test battery, aiming to explore their cognitive profile across a range of executive subcomponents. Results revealed impairments with respect to initiation, reasoning and planning. In summary, the present investigation shows that PD is associated with a differential executive impairment pattern which is (partly) related to disease characteristics and affective variables.

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Author information

Authors and Affiliations

  1. Faculty of Psychology, Institute of Cognitive Neuroscience, GAFO 05/607, Ruhr-University Bochum, D-44780, Bochum, Germany

    J. Uekermann, I. Daum, M. Bielawski, S. Muhlack, S. Peters, H. Przuntek & T. Mueller

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  1. J. Uekermann
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  2. I. Daum
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  3. M. Bielawski
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  4. S. Muhlack
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  5. S. Peters
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  6. H. Przuntek
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  7. T. Mueller
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Editors and Affiliations

  1. Neurologische Klinik, St. Josef Hospital, Gudrunstraße 56, 44791, Bochum, Germany

    Th. Müller

  2. Klinik und Poliklinik für Psychiatrie und Psychotherapie, Füchsleinstraße 15, 97080, Würzburg, Germany

    P. Riederer

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© 2004 Springer-Verlag Wien

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Uekermann, J. et al. (2004). Differential executive control impairments in early Parkinson’s disease. In: Müller, T., Riederer, P. (eds) Focus on Extrapyramidal Dysfunction. Journal of Neural Transmission. Supplementa, vol 68. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0579-5_5

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  • DOI: https://doi.org/10.1007/978-3-7091-0579-5_5

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-21114-4

  • Online ISBN: 978-3-7091-0579-5

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