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Nociception and TRP Channels

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Book cover Transient Receptor Potential (TRP) Channels

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 179))

Abstract

Pain is initiated when noxious stimuli excite the peripheral terminals of specialized primary afferent neurons called nociceptors. Many molecules are involved in conversion of the noxious stimuli to the electrical signals in the nociceptor endings. Among them, TRP channels play important roles in detecting noxious stimuli.

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Authors and Affiliations

  1. Section of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, 444-8787, Okazaki, Japan

    M. Tominaga

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  1. M. Tominaga
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  1. Experimentele und Klinische, Pharmakologie und Toxikologie, Universität des Saarlandes, Gebäude 46, 66421, Homburg, Deutschland

    Veit Flockerzi

  2. Laboratorium voor Fysiologie, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, 3000, Leuven, België

    Bernd Nilius

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Tominaga, M. (2007). Nociception and TRP Channels. In: Flockerzi, V., Nilius, B. (eds) Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology, vol 179. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-34891-7_29

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