Skip to main content

Effects of Sulfonylureas on the Pancreas

  • Chapter
Book cover The Diabetic Pancreas

Abstract

In 1942 Janbon and his collaboratorst1,2 reported that during clinical tests with p-aminobenzenesulfamidoisopropylthiodiazole (2254 RP), its administration in high doses (up to 12 g/day orally) produced, in some patients with typhoid fever, hypoglycemic manifestations and sometimes fatalities.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Janbon, M., Chaptal, J., Vedel, A., and Schaap, J .: Montpellier Méd, 21–22: 441, 1942.

    Google Scholar 

  2. Janbon, M., Lazergues, P., and Metropolitanski, J. H.: Montpellier Méd, 21–22: 4891942.

    Google Scholar 

  3. Loubatières, A., Goldstein, L., Metropolitanski, J., and Schaap, J.: In: 43ème Congrè Médecins Aliénistes et Neurologistes de France et des Pays de Langue Francaise. Edited by Masson. Montpellier, Paris. 1942, p. 415.

    Google Scholar 

  4. Loubatières, A.: C. R. Soc. Biol, 138: 766, 1944.

    Google Scholar 

  5. Loubatières, A.: Thèse Doctorat ès–Sciences naturelles. Montpellier, Causse, Graille et Castelnau, 1946.

    Google Scholar 

  6. Loubatières, A.: Arch. Int. Physiol, 54: 174, 1946.

    Article  Google Scholar 

  7. Loubatières, A.: Arch. Int. Pharmacodyn, 140: 127, 1962.

    Google Scholar 

  8. Loubatières, A.: In: Perspectives in Biology. Edited by C. F. Cori, V. G. Foglia, L. F. Leloir, and S. Ochoa. Elsevier, Amsterdam, 1963, p. 117.

    Google Scholar 

  9. Loubatières, A.: In: Diabetes Mellitus. Edited by K. Oberdisse and K. Jahnke. Georg Thieme Verlag, Stuttgart, 1958, p. 279.

    Google Scholar 

  10. Fruteau de Laclos, C., and Loubatières, A.: Bull. Assoc. Anat, 106: 261, 1960.

    Google Scholar 

  11. Loubatières, A.: In: The Structure and Metabolism of the Pancreatic Islet. Edited by S. E. Brolin, B. Hellman, and H. Knutson. Pergamon Press, Oxford, 1964, p. 437.

    Google Scholar 

  12. Loubatières, A., Bouyard, P., Fruteau de Laclos, C., Sassine, A., and Alric, R.: C. R. Soc. Biol, 150: 1601, 1956.

    Google Scholar 

  13. Houssay, B. A., Penhos, J. C., Urgoiti, E., Teodosio, N., Apelbaum, J., and Bowket, J.: Ann. N.Y. Acad. Sci, 71: 25, 1957.

    Article  PubMed  CAS  Google Scholar 

  14. Loubatières, A.: Presse Méd, 63: 1701, 1955.

    PubMed  Google Scholar 

  15. Loubatières, A.: Ann. N.Y. Acad. Sci, 71: 4, 1957.

    Article  PubMed  Google Scholar 

  16. Loubatières, A.: In: Pharmacokinetics and Mode of Action of Oral Hypoglycemic Agents. Edited by A. Loubatières and A. E. Renold. Acta Diabetologica Latina, Milan, Suppl. 1, 1969, p. 20.

    Google Scholar 

  17. Loubatières, A.: In: Pharmacokinetics and Mode of Action of Oral Hypoglycemic Agents. Edited by A. Loubatières and A. E. Renold. Acta Diabetologica Latina, Milan, Suppl. 1, 1969, p. 216.

    Google Scholar 

  18. Franke, J., and Fuchs, J.: Dtsch. Med. Wachenschr, 80: 1449, 1955.

    Article  CAS  Google Scholar 

  19. Bertram, F., Bendfeldt, E., and Otto, H.: Dtsch. Med. Wochenschr, 80: 1455, 1955.

    Article  PubMed  CAS  Google Scholar 

  20. Loubatières, A.: C. R. Acad. Sci, 241: 1422, 1955.

    Google Scholar 

  21. Loubatières, A.: Méd. Hyg, 13: 495, 1955.

    Google Scholar 

  22. Loubatières, A., Bouyard, P., and Fruteau de Laclos, C.: Sem. Hôp. Paris, 32:RM 47, 1956.

    Google Scholar 

  23. Bänder, A., Creutzfeldt, W., Dorfmüller, T., Ehrhart, H., Marx, R., Maske, H., Meier, W., Mohnike, G., Pfeiffer, E. F., Schlaginweit, S., Schöffling, K., Scholz, J., Seidler, I., Steigerwald, H., Stich, W., Stötter, G., and Ulrich, H.: Dtsch. Med. Wochenschr, 81: 823, 1956.

    Article  PubMed  Google Scholar 

  24. Loubatières, A.: Ann. N.Y. Acad. Sci, 71: 192, 1957.

    Article  Google Scholar 

  25. Loubatières, A.: Diabetes, 6: 408, 1957.

    PubMed  Google Scholar 

  26. Loubatières, A., Mariani, M. M., Ribes, G., and Chapal, J.: C.R. Soc. Biol, 169: 1392, 1971.

    Google Scholar 

  27. Loubatières, A., Loubatières–Mariani, M. M., Ribes, G., and Chapal, J.: Diabetologia, 9: 79, 1973.

    Google Scholar 

  28. Levine, R., and Fritz, I. B.: Diabetes, 5: 209, 1956.

    PubMed  CAS  Google Scholar 

  29. Loubatières, A., Alric, R., Loubatières–Mariani, M. M., and Puech, R.: C. R. Soc. Biol, 166: 1761, 1972.

    Google Scholar 

  30. Loubatières, A., Loubatières–Mariani, M. M., Ribes, G., and Alrie, R.: C.R. Soc. Biol, 166: 1757, 1972.

    Google Scholar 

  31. Loubatières, A., Loubatières–Mariani, M. M., Alric, R., and Ribes, G.: Diabetologia, 10: 271, 1974.

    PubMed  Google Scholar 

  32. Loubatières, A., Loubatières–Mariani, M. M., Chapal, J., and Blayac, J. P.: C.R. Soc. Biol, 169: 1568, 1975.

    Google Scholar 

  33. Volk, B. W., Goldner, M. G., Weisenfeld, S., and Lazarus, S. S.: Ann. N. Y. Acad. Sci, 71: 141, 1957.

    Article  CAS  Google Scholar 

  34. Williamson, J. R., Lacy, P. E., and Grisham, J. W.: Diabetes, 10: 460, 1961.

    PubMed  CAS  Google Scholar 

  35. Lacy, P. E.: Diabetes, 11: 509, 1962.

    PubMed  CAS  Google Scholar 

  36. Lacy, P. E.: In: Mechanism and Regulation of Insulin Secretion. Edited by R. Levine and E. F. Pfeiffer. Acta Diabetologica Latina, Milan, Suppl. 1, 1968, p. 436.

    Google Scholar 

  37. Orci, L., Stauffacher, W., Don Beaven, Lambert, A. E., Renold, A. E., and Rouiller, C.: In: Pharmacokinetics and Mode of Action of Oral Hypoglycemic Agents. Edited by A. Loubatières and A. E. Renold. Acta Diabetologica Latina, Milan, Suppl. 1, 1969, p. 271.

    Google Scholar 

  38. Pfeiffer, E. F., Renold, A. E., Martin, D. B., Dagenais, Y., Meakin, J. W., Nelson, D. H., Shoemaker, G., and Thorn, G. W.: In: Diabetes Mellitus. Edited by K. Oberdisse and K. Jahnke. Georg Thieme Verlag, Stuttgart, 1958, p. 298.

    Google Scholar 

  39. Pfeiffer, E. F., Schöffling, K., and Ditschuneit, H.: In: Handbuch des Diabetes Mellitus. Edited by E. F. Pfeiffer. J. F. Lehmanns Verlag, Munich, 1969, p. 636.

    Google Scholar 

  40. Yalow, R. W., Black, H., Villazon, M., and Berson, S. A.: Diabetes, 9: 356, 1960.

    PubMed  CAS  Google Scholar 

  41. Loubatières, A., and Mariani, M. M.: C.R. Acad. Sci, 265: 643, 1967.

    Google Scholar 

  42. Loubatières, A., Mariani, M. M., Ribes, G., De Malbosc, H., and Chapal, J. Diabetologia, 5: 1, 1969.

    Article  PubMed  Google Scholar 

  43. Loubatières, A.: In: Medecine et Hygiène. Edited by B. Glasson and A. Benakis. Geneva, 1974, p. 179.

    Google Scholar 

  44. Loubatières, A., Loubatières–Mariani, M. M., Alric, R., Ribes, G., Sorel, G., and Tarasco, A.: Diab. Mét, 1: 13, 1975.

    Article  Google Scholar 

  45. Grodsky, G. M., Curry, D., Landahl, A., and Bennett, L.: In: Pharmacokinetics and Mode of Action of Oral Hypoglycemic Agents. Edited by A. Loubatières and A. E. Renold. Acta Diabetologica Latina, Milan, Suppl. 1, 1969, p. 554.

    Google Scholar 

  46. Loubatières, A., Mariani, M.M., and Chapal, J.: C.R. Acad. Sci, 267: 123, 1968.

    Google Scholar 

  47. Loubatières, A., Mariani, M. M., and Chapal, J .: Diabetologia, 6: 457, 1970.

    Article  Google Scholar 

  48. Loubatières–Mariani, M. M., Loubatières, A., and Chapal, J.: Diabetologia, 9: 152, 1973.

    Article  Google Scholar 

  49. Loubatières, A., Mariani, M. M., and Chapal, J.: C.R. Acad. Sci, 269: 1460, 1969.

    Google Scholar 

  50. Loubatières, A., Mariani, M. M., and Chapal, J.: Diabetologia, 6: 533, 1970.

    Article  PubMed  Google Scholar 

  51. Loubatières, A., Mariani, M. M., Ribes, G., and Alric, R.: Acta Diabetologia Latina, 10: 261, 1973.

    Article  Google Scholar 

  52. Loubatières, A.: In: Mechanism and Regulation of Insulin Secretion. Edited by R. Levine and E. F. Pfeiffer. Acta Diabetologia Latina, Milan, Suppl. 1, 1968, p. 220.

    Google Scholar 

  53. Mariani, M. M.: In: Pharmacokinetics and Mode of Action of Oral Hypoglycemic Agents. Edited by A. Loubatières and A. E. Renold. Acta Diabetologia Latina, Milan, Suppl. 1, 1969, p. 256.

    Google Scholar 

  54. Pfeiffer, E. F.: In: Pharmacokinetics and Mode of Action of Oral Hypoglycemic Agents. Edited by A. Loubatières and A. E. Renold. Acta Diabetologia Latina, Milan, Suppl. 1, 1969, p. 477.

    Google Scholar 

  55. Loubatières, A., Loubatières–Mariani, M. M., and Chapal, J.: G.R. Sec. Biol, 167: 1892, 1973.

    Google Scholar 

  56. Levey, G. E., Schmidt, W. M. I., and Mintz, D. H.: Metabolism, 21: 93, 1972.

    Article  PubMed  CAS  Google Scholar 

  57. Kuo, W. N., Hodgins, D. S., and Kuo, J. F.: J . Biol. Chem, 248: 2705, 1973.

    PubMed  CAS  Google Scholar 

  58. Rosen, O. M., Hirsch, A. M., and Goren, E. N.: Arch. Biochem. Biophys, 146: 660, 1971.

    Article  PubMed  CAS  Google Scholar 

  59. Ozer, A., and Sharp, G. W. G.: Europ J . Pharmacol. 22: 227, 1973.

    Article  CAS  Google Scholar 

  60. Bowen, V. and Lazarus, N. R.: Biochem. J, 142: 385, 1974.

    PubMed  CAS  Google Scholar 

  61. Matthews, E. K., and Dean, P. M.: In: The Structure and Metabolism of the Pancreatic Islets. Edited by S. Falkmer, B. Hellman, I. B. Taljedal. Pergamon Press, Oxford, 1970, p. 305.

    Google Scholar 

  62. Meissner, H. P., and Atwater, I. J.: Horm. Metab. Res, 8: 11, 1976.

    Article  PubMed  CAS  Google Scholar 

  63. Hellman, B., Idahl, L. A., and Danielsson, A.: Diabetes, 18: 509, 1969.

    PubMed  CAS  Google Scholar 

  64. Hellman, B., Sehlin, J., and Taljedal, I. B.: Diabetologia, 9: 210, 1973.

    Article  PubMed  CAS  Google Scholar 

  65. Malaisse, W. J., Mahy, M., and Malaisse–Lagae, F.: Arch. Int. Pharmacodyn, 192: 205, 1971.

    PubMed  CAS  Google Scholar 

  66. Alric, R., Manteghetti, M., Puech, R., Lignon, F., and Loubatières, A.: C. R. Acad. Sci, 281: 2029, 1975.

    CAS  Google Scholar 

  67. Alric, R., Manteghetti, M., Puech, R., Lignon, F., and Loubatières, A.: C. R . Acad. Sci, 283: 283, 1976.

    CAS  Google Scholar 

  68. Somogyi, J., Vincze, I., Willig, F., and Schmidt, F. H.: Horenn. Metab. Res, 6: 181, 1974.

    Article  CAS  Google Scholar 

  69. Loubatières, A.: Israel J . Med. Sci, 8: 682, 1972.

    Google Scholar 

  70. Loubatières, A., Mariani, M. M., Alric, R., Ribes, G., De Malbosc, H., and Houareau, M. H.: Diabetologia, 5: 219, 1969.

    Article  PubMed  Google Scholar 

  71. Chick, W. L.: Diabetes, 22: 687, 1973.

    PubMed  CAS  Google Scholar 

  72. Andersson, A.: Endocrinology, 96: 1051, 1975.

    Article  CAS  Google Scholar 

  73. Loubatières, A.: C. R. Soc. Biol, 138: 830, 1944.

    Google Scholar 

  74. Loubatières, A., Mariani, M. M., and Alric, R.: Ann. N.Y. Acad. Sci, 150: 226, 1968.

    Article  PubMed  Google Scholar 

  75. Loubatières, A., Mariani, M. M., Alric, R., and Chapal, J.: In: Tolbutamide after Ten Years. Edited by W. J. H. Butterfield and W. Van Westering. Excerpta Medica, New York, 1967, p. 100.

    Google Scholar 

  76. Seltzer, H. S., and Crout, J. R.: Diabetes, 15: 523, 1966.

    Google Scholar 

  77. Frerichs, H., Creutzfeldt, C., and Creutzfeldt, W.: In: Mechanism and Regulation of Insulin Secretion. Edited by R. Levine and E. F. Pfeiffer. Acta Diabetologica Latina, Milan, Suppl. 1, 1968, p. 105.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1977 Plenum Press, New York

About this chapter

Cite this chapter

Loubatières, A. (1977). Effects of Sulfonylureas on the Pancreas. In: Volk, B.W., Wellmann, K.F. (eds) The Diabetic Pancreas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2325-9_20

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-2325-9_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2327-3

  • Online ISBN: 978-1-4684-2325-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics