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Tin-Free Radical Reactions Mediated by Organoboron Compounds

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Radicals in Synthesis I

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 263))

Abstract

The development of tin-free methods to run radical reactions is crucial for their applications in industrial processes as well as in drug discovery projects. Within the last 10 years, organoboron compounds have demonstrated that they represent one of the most attractive approach to substitute tin reagents in radical process. This review summarizes the results obtained with organoboron compounds as a source of alkyl radicals. Four different strategies are described, i.e., the use of organoboranes as radical initiators, as a source of alkyl radicals, as chain transfer reagents, and finally as reducing agents.

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  1. Departement für Chemie und Biochemie, Universität Bern, Freiestrasse 3, 3012, Bern, Switzerland

    Vincent Darmency & Philippe Renaud

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  1. Vincent Darmency
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  2. Philippe Renaud
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Correspondence to Philippe Renaud .

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Andreas Gansäuer

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Darmency, V., Renaud, P. Tin-Free Radical Reactions Mediated by Organoboron Compounds. In: Gansäuer, A. (eds) Radicals in Synthesis I. Topics in Current Chemistry, vol 263. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_030

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