Regular ArticleA Retrotransposon-Derived Gene, PEG10, Is a Novel Imprinted Gene Located on Human Chromosome 7q21☆
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Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL
2022, Blood AdvancesCitation Excerpt :We recently found that the ASNS gene was methylated in an allele-specific manner in B-cell precursor ALL (BCP-ALL) cell lines and in patient samples from childhood BCP-ALL.17 Allele-specific methylation is a hallmark of genomic imprinting, and the ASNS gene is located adjacent to the 7q21 imprinted gene clusters.18,19 Of note, in BCP-ALL, the methylation status of the ASNS gene was associated with an aberrant methylation of the 7q21 imprinted gene cluster.17
Targeting PEG10 as a novel therapeutic approach to overcome CDK4/6 inhibitor resistance in breast cancer
2023, Journal of Experimental and Clinical Cancer Research
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Sequence data from this article have been deposited with the EMBL/GenBank Data Libraries under Accession No. AB049834.
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