Biochemical and Biophysical Research Communications
Regular ArticleBoswellic Acids Activate p42MAPK and p38 MAPK and Stimulate Ca2+ Mobilization☆,☆☆
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This study was supported by grants from the EU (QLG1-CT-2001-01521).
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Abbreviations used: AB, antibody; A-β-BA, 3-O-acetyl-β-boswellic acid; AKBA, 3-O-acetyl-11-keto-β-boswellic acid; KBA, 11-keto-β-boswellic acid; β-BA, β-boswellic acid; fMLP, N-formyl-methionyl-leucyl-phenylalanine; JNK, c-jun NH2-terminal kinase; MAPK, mitogen-activated protein kinase; MBP, myelin basic protein; MEK, MAPK kinase; PAF, platelet-activating factor; PBS, phosphate-buffered saline, pH 7.4; PG buffer, PBS containing 1 mg/ml glucose; PGC buffer, PBS containing 1 mg/ml glucose and 1 mM CaCl2; PI 3-K, phosphatidylinositol 3-kinase; PKC, protein kinase C; PMNL, polymorphonuclear leukocytes; SDS-b, 2× SDS–PAGE sample loading buffer; WB, Western blotting.
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