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Cochrane Database of Systematic Reviews Protocol - Intervention

Surfactant therapy via brief tracheal catheterization in preterm infants with or at risk of respiratory distress syndrome

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Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

In non‐intubated preterm infants with, or at risk of, RDS to compare surfactant administration via brief tracheal catheterization with:

  1. continuation of non‐invasive respiratory support (CPAP) or high flow nasal cannulae (HFNC) without surfactant administration;

  2. intubation and surfactant administration through an ETT with or without intent to remove the ETT immediately after the procedure;

Additionally:

  • to compare different methods of surfactant administration via brief tracheal catheterization with each other.