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Planta Med 1996; 62(1): 67-69
DOI: 10.1055/s-2006-957804
Letter

© Georg Thieme Verlag Stuttgart · New York

Antifungal and Antibacterial Chalcones from Myrica serrata

Stefan Gafner1 , Jean-Luc Wolfender1 , Stephen Mavi2 , Kurt Hostettmann1
  • 1Institut de Pharmacognosie et Phytochimie, Université de Lausanne, B. E. P., CH-1015 Lausanne, Switzerland
  • 2National Herbarium and National Botanic Garden, P.O. Box 8100, Causeway, Harare, Zimbabwe
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Publication History

1995

1995

Publication Date:
04 January 2007 (online)

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Abstract

The dichloromethane extract of the leaves of Myrica serrata inhibits growth of Cladosporium cucumerinum, Bacillus subtilis, and Escherichia coli on TLC plates. Activity-guided fractionation led to the isolation of 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethyl-chalcone (1), 2′,4′-dihydroxy-6′-methoxy-5′-methyl-chalcone (aurentiacin A) (2), 2′,6′-dihydroxy-4′-methoxy-3′,5′-dimethyldihydrochalcone (3), 2′-hydroxy-4′,6′-dimethoxy-3′-methyldihydrochalcone (4), and 2′, 6′-dihydroxy-4′-methoxy-3′-methyldihydrochalcone (5). In addition, the flavanones demethoxymatteucinol (6) and cryptostrobin (7) were also identified.

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