Review article
Does acupuncture improve the outcome of in vitro fertilization? Guidance for future trials

https://doi.org/10.1016/j.eujim.2012.07.978Get rights and content
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Abstract

Introduction

The comprehensive review was to appraise the current evidence from both randomized and non-randomized trials by using both Chinese and western databases and to highlight the issues which could guide future trial design. Many infertile couples have chosen acupuncture as an adjunct when they undergo in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment. More than forty trials have emerged since the first clinical research published in 1999 explored the effects of acupuncture on the outcomes of IVF. However, the current evidence makes it difficult for clinical practitioners and patients to make a decision on whether to choose acupuncture as an adjunct when undergoing IVF or ICSI treatment.

Methodology

A total of thirty-three randomized and 5 non-randomized controlled trials were included in the review.

Results

Based on this comprehensive review and analysis of all the relevant trials, the authors identify the factors which have contributed to these inconsistencies, and which should be considered in the design of future studies.

Discussion/conclusions

These items included in the review could provide useful recommendations and guidelines, which will in turn promote better trial design and improve the evidence base for the use of acupuncture for IVF.

Keywords

Acupuncture
In vitro fertilization (IVF)
Intracytoplasmic sperm injection (ICSI)

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1

Both authors contributed equally to the study.